Karbapenem dirençli Pseudomonas ve Acinetobacter türlerinde MBL üretiminin saptanması ve risk faktörlerinin değerlendirilmesi.

Purpose: To investigate the frequency of MBLs in Pseudomonas and Acinetobacter species with E-test, to determine risk factors evaluate demographic clinical features infected patients. Materials methods: Imipenem or meropenem resistance isolated from several samples conventional methods were evaluated imipenem EDTA E-test presence Metallo-β-lactameses MBL was examined. Several isolates screened for VIM-1, VIM-2, IMP-1, IMP-2 a PCR test. Results: Of 46 carbapenem resistant isolates, 41 (89%), as well 19 5 (26%) had positivity imipenem-EDTA E-test. A history Intensive Care Unit stay, mechanical ventilation cephalosporin use found be significant respect production. Conclusion: Detection production especially ICU patients is prime importance control infection rapidly effectively, which contribute prevention outbreaks.